diff --git a/config.template.toml b/config.template.toml
index 744dfc7953a4..331663c619f4 100644
--- a/config.template.toml
+++ b/config.template.toml
@@ -17,6 +17,12 @@
 #modal_api_token_id = ""
 #modal_api_token_secret = ""
 
+# API key for Daytona
+#daytona_api_key = ""
+
+# Daytona Target
+#daytona_target = ""
+
 # Base path for the workspace
 workspace_base = "./workspace"
 
diff --git a/openhands/core/config/app_config.py b/openhands/core/config/app_config.py
index 5965f06480c8..7abf0936f86b 100644
--- a/openhands/core/config/app_config.py
+++ b/openhands/core/config/app_config.py
@@ -75,6 +75,9 @@ class AppConfig(BaseModel):
     file_uploads_restrict_file_types: bool = Field(default=False)
     file_uploads_allowed_extensions: list[str] = Field(default_factory=lambda: ['.*'])
     runloop_api_key: SecretStr | None = Field(default=None)
+    daytona_api_key: SecretStr | None = Field(default=None)
+    daytona_api_url: str = Field(default='https://app.daytona.io/api')
+    daytona_target: str = Field(default='us')
     cli_multiline_input: bool = Field(default=False)
     conversation_max_age_seconds: int = Field(default=864000)  # 10 days in seconds
 
diff --git a/openhands/core/logger.py b/openhands/core/logger.py
index 2f830c655a00..82ce45a1fec3 100644
--- a/openhands/core/logger.py
+++ b/openhands/core/logger.py
@@ -243,6 +243,7 @@ def filter(self, record):
             'modal_api_token_secret',
             'llm_api_key',
             'sandbox_env_github_token',
+            'daytona_api_key',
         ]
 
         # add env var names
diff --git a/openhands/runtime/__init__.py b/openhands/runtime/__init__.py
index 5ddf881fcfa3..0590d62b7c33 100644
--- a/openhands/runtime/__init__.py
+++ b/openhands/runtime/__init__.py
@@ -1,4 +1,5 @@
 from openhands.core.logger import openhands_logger as logger
+from openhands.runtime.impl.daytona.daytona_runtime import DaytonaRuntime
 from openhands.runtime.impl.docker.docker_runtime import (
     DockerRuntime,
 )
@@ -24,6 +25,8 @@ def get_runtime_cls(name: str):
         return RunloopRuntime
     elif name == 'local':
         return LocalRuntime
+    elif name == 'daytona':
+        return DaytonaRuntime
     else:
         raise ValueError(f'Runtime {name} not supported')
 
diff --git a/openhands/runtime/impl/daytona/README.md b/openhands/runtime/impl/daytona/README.md
new file mode 100644
index 000000000000..dfaa7e3dc02f
--- /dev/null
+++ b/openhands/runtime/impl/daytona/README.md
@@ -0,0 +1,24 @@
+# Daytona Runtime
+
+[Daytona](https://www.daytona.io/) is a platform that provides a secure and elastic infrastructure for running AI-generated code. It provides all the necessary features for an AI Agent to interact with a codebase. It provides a Daytona SDK with official Python and TypeScript interfaces for interacting with Daytona, enabling you to programmatically manage development environments and execute code.
+
+## Getting started
+
+1. Sign in at https://app.daytona.io/
+
+1. Generate and copy your API key
+
+1. Set the following environment variables before running the OpenHands app on your local machine or via a `docker run` command:
+
+```bash
+    RUNTIME="daytona"
+    DAYTONA_API_KEY="<your-api-key>"
+```
+Optionally, if you don't want your sandboxes to default to the US region, set:
+
+```bash
+    DAYTONA_TARGET="eu"
+```
+
+## Documentation
+Read more by visiting our [documentation](https://www.daytona.io/docs/) page.
diff --git a/openhands/runtime/impl/daytona/daytona_runtime.py b/openhands/runtime/impl/daytona/daytona_runtime.py
new file mode 100644
index 000000000000..437f6eeebf52
--- /dev/null
+++ b/openhands/runtime/impl/daytona/daytona_runtime.py
@@ -0,0 +1,262 @@
+import json
+from typing import Callable
+
+import tenacity
+from daytona_sdk import (
+    CreateWorkspaceParams,
+    Daytona,
+    DaytonaConfig,
+    SessionExecuteRequest,
+    Workspace,
+)
+
+from openhands.core.config.app_config import AppConfig
+from openhands.events.stream import EventStream
+from openhands.runtime.impl.action_execution.action_execution_client import (
+    ActionExecutionClient,
+)
+from openhands.runtime.plugins.requirement import PluginRequirement
+from openhands.runtime.utils.command import get_action_execution_server_startup_command
+from openhands.utils.async_utils import call_sync_from_async
+from openhands.utils.tenacity_stop import stop_if_should_exit
+
+WORKSPACE_PREFIX = 'openhands-sandbox-'
+
+
+class DaytonaRuntime(ActionExecutionClient):
+    """The DaytonaRuntime class is a DockerRuntime that utilizes Daytona workspace as a runtime environment."""
+
+    _sandbox_port: int = 4444
+    _vscode_port: int = 4445
+
+    def __init__(
+        self,
+        config: AppConfig,
+        event_stream: EventStream,
+        sid: str = 'default',
+        plugins: list[PluginRequirement] | None = None,
+        env_vars: dict[str, str] | None = None,
+        status_callback: Callable | None = None,
+        attach_to_existing: bool = False,
+        headless_mode: bool = True,
+    ):
+        assert config.daytona_api_key, 'Daytona API key is required'
+
+        self.config = config
+        self.sid = sid
+        self.workspace_id = WORKSPACE_PREFIX + sid
+        self.workspace: Workspace | None = None
+        self._vscode_url: str | None = None
+
+        daytona_config = DaytonaConfig(
+            api_key=config.daytona_api_key.get_secret_value(),
+            server_url=config.daytona_api_url,
+            target=config.daytona_target,
+        )
+        self.daytona = Daytona(daytona_config)
+
+        # workspace_base cannot be used because we can't bind mount into a workspace.
+        if self.config.workspace_base is not None:
+            self.log(
+                'warning',
+                'Workspace mounting is not supported in the Daytona runtime.',
+            )
+
+        super().__init__(
+            config,
+            event_stream,
+            sid,
+            plugins,
+            env_vars,
+            status_callback,
+            attach_to_existing,
+            headless_mode,
+        )
+
+    def _get_workspace(self) -> Workspace | None:
+        try:
+            workspace = self.daytona.get_current_workspace(self.workspace_id)
+            self.log(
+                'info', f'Attached to existing workspace with id: {self.workspace_id}'
+            )
+        except Exception:
+            self.log(
+                'warning',
+                f'Failed to attach to existing workspace with id: {self.workspace_id}',
+            )
+            workspace = None
+
+        return workspace
+
+    def _get_creation_env_vars(self) -> dict[str, str]:
+        env_vars: dict[str, str] = {
+            'port': str(self._sandbox_port),
+            'PYTHONUNBUFFERED': '1',
+            'VSCODE_PORT': str(self._vscode_port),
+        }
+
+        if self.config.debug:
+            env_vars['DEBUG'] = 'true'
+
+        return env_vars
+
+    def _create_workspace(self) -> Workspace:
+        workspace_params = CreateWorkspaceParams(
+            id=self.workspace_id,
+            language='python',
+            image=self.config.sandbox.runtime_container_image,
+            public=True,
+            env_vars=self._get_creation_env_vars(),
+        )
+        workspace = self.daytona.create(workspace_params)
+        return workspace
+
+    def _get_workspace_status(self) -> str:
+        assert self.workspace is not None, 'Workspace is not initialized'
+        assert (
+            self.workspace.instance.info is not None
+        ), 'Workspace info is not available'
+        assert (
+            self.workspace.instance.info.provider_metadata is not None
+        ), 'Provider metadata is not available'
+
+        provider_metadata = json.loads(self.workspace.instance.info.provider_metadata)
+        return provider_metadata.get('status', 'unknown')
+
+    def _construct_api_url(self, port: int) -> str:
+        assert self.workspace is not None, 'Workspace is not initialized'
+        assert (
+            self.workspace.instance.info is not None
+        ), 'Workspace info is not available'
+        assert (
+            self.workspace.instance.info.provider_metadata is not None
+        ), 'Provider metadata is not available'
+
+        node_domain = json.loads(self.workspace.instance.info.provider_metadata)[
+            'nodeDomain'
+        ]
+        return f'https://{port}-{self.workspace.id}.{node_domain}'
+
+    def _get_action_execution_server_host(self) -> str:
+        return self.api_url
+
+    def _start_action_execution_server(self) -> None:
+        assert self.workspace is not None, 'Workspace is not initialized'
+
+        self.workspace.process.exec(
+            f'mkdir -p {self.config.workspace_mount_path_in_sandbox}'
+        )
+
+        start_command: list[str] = get_action_execution_server_startup_command(
+            server_port=self._sandbox_port,
+            plugins=self.plugins,
+            app_config=self.config,
+            override_user_id=1000,
+            override_username='openhands',
+        )
+        start_command_str: str = ' '.join(start_command)
+
+        self.log(
+            'debug',
+            f'Starting action execution server with command: {start_command_str}',
+        )
+
+        exec_session_id = 'action-execution-server'
+        self.workspace.process.create_session(exec_session_id)
+        self.workspace.process.execute_session_command(
+            exec_session_id,
+            SessionExecuteRequest(command='cd /openhands/code', var_async=True),
+        )
+
+        exec_command = self.workspace.process.execute_session_command(
+            exec_session_id,
+            SessionExecuteRequest(command=start_command_str, var_async=True),
+        )
+
+        self.log('debug', f'exec_command_id: {exec_command.cmd_id}')
+
+    @tenacity.retry(
+        stop=tenacity.stop_after_delay(120) | stop_if_should_exit(),
+        wait=tenacity.wait_fixed(1),
+        reraise=(ConnectionRefusedError,),
+    )
+    def _wait_until_alive(self):
+        super().check_if_alive()
+
+    async def connect(self):
+        self.send_status_message('STATUS$STARTING_RUNTIME')
+
+        if self.attach_to_existing:
+            self.workspace = await call_sync_from_async(self._get_workspace)
+
+        if self.workspace is None:
+            self.send_status_message('STATUS$PREPARING_CONTAINER')
+            self.workspace = await call_sync_from_async(self._create_workspace)
+            self.log('info', f'Created new workspace with id: {self.workspace_id}')
+
+        if self._get_workspace_status() == 'stopped':
+            self.log('info', 'Starting Daytona workspace...')
+            await call_sync_from_async(self.workspace.start)
+
+        self.api_url = await call_sync_from_async(
+            self._construct_api_url, self._sandbox_port
+        )
+
+        if not self.attach_to_existing:
+            await call_sync_from_async(self._start_action_execution_server)
+            self.log(
+                'info',
+                f'Container started. Action execution server url: {self.api_url}',
+            )
+
+        self.log('info', 'Waiting for client to become ready...')
+        self.send_status_message('STATUS$WAITING_FOR_CLIENT')
+        await call_sync_from_async(self._wait_until_alive)
+
+        if not self.attach_to_existing:
+            await call_sync_from_async(self.setup_initial_env)
+
+        self.log(
+            'info',
+            f'Container initialized with plugins: {[plugin.name for plugin in self.plugins]}',
+        )
+
+        if not self.attach_to_existing:
+            self.send_status_message(' ')
+        self._runtime_initialized = True
+
+    def close(self):
+        super().close()
+
+        if self.attach_to_existing:
+            return
+
+        if self.workspace:
+            self.daytona.remove(self.workspace)
+
+    @property
+    def vscode_url(self) -> str | None:
+        if self._vscode_url is not None:  # cached value
+            return self._vscode_url
+        token = super().get_vscode_token()
+        if not token:
+            self.log(
+                'warning', 'Failed to get VSCode token while trying to get VSCode URL'
+            )
+            return None
+        if not self.workspace:
+            self.log(
+                'warning', 'Workspace is not initialized while trying to get VSCode URL'
+            )
+            return None
+        self._vscode_url = (
+            self._construct_api_url(self._vscode_port)
+            + f'/?tkn={token}&folder={self.config.workspace_mount_path_in_sandbox}'
+        )
+
+        self.log(
+            'debug',
+            f'VSCode URL: {self._vscode_url}',
+        )
+
+        return self._vscode_url
diff --git a/poetry.lock b/poetry.lock
index b7b7f8f689d9..c0151ab7545e 100644
--- a/poetry.lock
+++ b/poetry.lock
@@ -1507,6 +1507,47 @@ tests-numpy2 = ["Pillow (>=9.4.0)", "absl-py", "decorator", "elasticsearch (<8.0
 torch = ["torch"]
 vision = ["Pillow (>=9.4.0)"]
 
+[[package]]
+name = "daytona-api-client"
+version = "0.13.0"
+description = "Daytona Workspaces"
+optional = false
+python-versions = "*"
+groups = ["main"]
+files = [
+    {file = "daytona_api_client-0.13.0-py3-none-any.whl", hash = "sha256:c4d0dcb89a328c4d0a97d8f076eaf9a00ccc54a8b9f862f4b3302ae887d03c8f"},
+    {file = "daytona_api_client-0.13.0.tar.gz", hash = "sha256:d62b7cb14361b2706df192d2da7dc2b5d02be6fd4259e9433cf2bfdc5807416d"},
+]
+
+[package.dependencies]
+pydantic = ">=2"
+python-dateutil = ">=2.8.2"
+typing-extensions = ">=4.7.1"
+urllib3 = ">=1.25.3,<3.0.0"
+
+[[package]]
+name = "daytona-sdk"
+version = "0.9.1"
+description = "Python SDK for Daytona"
+optional = false
+python-versions = ">=3.7"
+groups = ["main"]
+files = [
+    {file = "daytona_sdk-0.9.1-py3-none-any.whl", hash = "sha256:cce6c90cd3d578747b3c388e24c811cb0b21ad125d34b32836c50059a577a12a"},
+    {file = "daytona_sdk-0.9.1.tar.gz", hash = "sha256:1e2f219f55130fc72d2f14a57d008b8d3e236d45294e0ca51e249106be5ca5de"},
+]
+
+[package.dependencies]
+daytona_api_client = ">=0.13.0,<1.0.0"
+environs = ">=9.5.0,<10.0.0"
+marshmallow = ">=3.19.0,<4.0.0"
+pydantic = ">=2.4.2,<3.0.0"
+python-dateutil = ">=2.8.2,<3.0.0"
+urllib3 = ">=2.0.7,<3.0.0"
+
+[package.extras]
+dev = ["black (>=22.0.0)", "isort (>=5.10.0)", "pydoc-markdown (>=4.8.2)"]
+
 [[package]]
 name = "debugpy"
 version = "1.8.12"
@@ -1731,6 +1772,28 @@ files = [
     {file = "english-words-2.0.1.tar.gz", hash = "sha256:a4105c57493bb757a3d8973fcf8e1dc05e7ca09c836dff467c3fb445f84bc43d"},
 ]
 
+[[package]]
+name = "environs"
+version = "9.5.0"
+description = "simplified environment variable parsing"
+optional = false
+python-versions = ">=3.6"
+groups = ["main"]
+files = [
+    {file = "environs-9.5.0-py2.py3-none-any.whl", hash = "sha256:1e549569a3de49c05f856f40bce86979e7d5ffbbc4398e7f338574c220189124"},
+    {file = "environs-9.5.0.tar.gz", hash = "sha256:a76307b36fbe856bdca7ee9161e6c466fd7fcffc297109a118c59b54e27e30c9"},
+]
+
+[package.dependencies]
+marshmallow = ">=3.0.0"
+python-dotenv = "*"
+
+[package.extras]
+dev = ["dj-database-url", "dj-email-url", "django-cache-url", "flake8 (==4.0.1)", "flake8-bugbear (==21.9.2)", "mypy (==0.910)", "pre-commit (>=2.4,<3.0)", "pytest", "tox"]
+django = ["dj-database-url", "dj-email-url", "django-cache-url"]
+lint = ["flake8 (==4.0.1)", "flake8-bugbear (==21.9.2)", "mypy (==0.910)", "pre-commit (>=2.4,<3.0)"]
+tests = ["dj-database-url", "dj-email-url", "django-cache-url", "pytest"]
+
 [[package]]
 name = "evaluate"
 version = "0.4.3"
@@ -3132,14 +3195,14 @@ zstd = ["zstandard (>=0.18.0)"]
 
 [[package]]
 name = "huggingface-hub"
-version = "0.28.1"
+version = "0.29.0"
 description = "Client library to download and publish models, datasets and other repos on the huggingface.co hub"
 optional = false
 python-versions = ">=3.8.0"
 groups = ["main", "evaluation", "llama-index"]
 files = [
-    {file = "huggingface_hub-0.28.1-py3-none-any.whl", hash = "sha256:aa6b9a3ffdae939b72c464dbb0d7f99f56e649b55c3d52406f49e0a5a620c0a7"},
-    {file = "huggingface_hub-0.28.1.tar.gz", hash = "sha256:893471090c98e3b6efbdfdacafe4052b20b84d59866fb6f54c33d9af18c303ae"},
+    {file = "huggingface_hub-0.29.0-py3-none-any.whl", hash = "sha256:c02daa0b6bafbdacb1320fdfd1dc7151d0940825c88c4ef89837fdb1f6ea0afe"},
+    {file = "huggingface_hub-0.29.0.tar.gz", hash = "sha256:64034c852be270cac16c5743fe1f659b14515a9de6342d6f42cbb2ede191fc80"},
 ]
 
 [package.dependencies]
@@ -4004,14 +4067,14 @@ files = [
 
 [[package]]
 name = "kubernetes"
-version = "32.0.0"
+version = "32.0.1"
 description = "Kubernetes python client"
 optional = false
 python-versions = ">=3.6"
 groups = ["llama-index"]
 files = [
-    {file = "kubernetes-32.0.0-py2.py3-none-any.whl", hash = "sha256:60fd8c29e8e43d9c553ca4811895a687426717deba9c0a66fb2dcc3f5ef96692"},
-    {file = "kubernetes-32.0.0.tar.gz", hash = "sha256:319fa840345a482001ac5d6062222daeb66ec4d1bcb3087402aed685adf0aecb"},
+    {file = "kubernetes-32.0.1-py2.py3-none-any.whl", hash = "sha256:35282ab8493b938b08ab5526c7ce66588232df00ef5e1dbe88a419107dc10998"},
+    {file = "kubernetes-32.0.1.tar.gz", hash = "sha256:42f43d49abd437ada79a79a16bd48a604d3471a117a8347e87db693f2ba0ba28"},
 ]
 
 [package.dependencies]
@@ -4786,7 +4849,7 @@ version = "3.26.1"
 description = "A lightweight library for converting complex datatypes to and from native Python datatypes."
 optional = false
 python-versions = ">=3.9"
-groups = ["evaluation", "llama-index"]
+groups = ["main", "evaluation", "llama-index"]
 files = [
     {file = "marshmallow-3.26.1-py3-none-any.whl", hash = "sha256:3350409f20a70a7e4e11a27661187b77cdcaeb20abca41c1454fe33636bea09c"},
     {file = "marshmallow-3.26.1.tar.gz", hash = "sha256:e6d8affb6cb61d39d26402096dc0aee12d5a26d490a121f118d2e81dc0719dc6"},
@@ -4933,14 +4996,14 @@ urllib3 = "*"
 
 [[package]]
 name = "mistune"
-version = "3.1.1"
+version = "3.1.2"
 description = "A sane and fast Markdown parser with useful plugins and renderers"
 optional = false
 python-versions = ">=3.8"
 groups = ["runtime"]
 files = [
-    {file = "mistune-3.1.1-py3-none-any.whl", hash = "sha256:02106ac2aa4f66e769debbfa028509a275069dcffce0dfa578edd7b991ee700a"},
-    {file = "mistune-3.1.1.tar.gz", hash = "sha256:e0740d635f515119f7d1feb6f9b192ee60f0cc649f80a8f944f905706a21654c"},
+    {file = "mistune-3.1.2-py3-none-any.whl", hash = "sha256:4b47731332315cdca99e0ded46fc0004001c1299ff773dfb48fbe1fd226de319"},
+    {file = "mistune-3.1.2.tar.gz", hash = "sha256:733bf018ba007e8b5f2d3a9eb624034f6ee26c4ea769a98ec533ee111d504dff"},
 ]
 
 [[package]]
@@ -8391,33 +8454,34 @@ pathspec = ">=0.10.1"
 
 [[package]]
 name = "scikit-image"
-version = "0.25.1"
+version = "0.25.2"
 description = "Image processing in Python"
 optional = false
 python-versions = ">=3.10"
 groups = ["evaluation"]
 files = [
-    {file = "scikit_image-0.25.1-cp310-cp310-macosx_10_9_x86_64.whl", hash = "sha256:40763a3a089617e6f00f92d46b3475368b9783588a165c2aa854da95b66bb4ff"},
-    {file = "scikit_image-0.25.1-cp310-cp310-macosx_12_0_arm64.whl", hash = "sha256:7c6b69f33e5512ee7fc53361b064430f146583f08dc75317667e81d5f8fcd0c6"},
-    {file = "scikit_image-0.25.1-cp310-cp310-manylinux_2_17_aarch64.manylinux2014_aarch64.whl", hash = "sha256:d9187347d115776ff0ddba3e5d2a04638d291b1a62e3c315d17b71eea351cde8"},
-    {file = "scikit_image-0.25.1-cp310-cp310-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:cdfca713979ad1873a4b55d94bb1eb4bc713f0c10165b261bf6f7e606f44a00c"},
-    {file = "scikit_image-0.25.1-cp310-cp310-win_amd64.whl", hash = "sha256:167fb146de80bb2a1493d1a760a9ac81644a8a5de254c3dd12a95d1b662d819c"},
-    {file = "scikit_image-0.25.1-cp311-cp311-macosx_10_9_x86_64.whl", hash = "sha256:c1bde2d5f1dfb23b3c72ef9fcdb2dd5f42fa353e8bd606aea63590eba5e79565"},
-    {file = "scikit_image-0.25.1-cp311-cp311-macosx_12_0_arm64.whl", hash = "sha256:5112d95cccaa45c434e57efc20c1f721ab439e516e2ed49709ddc2afb7c15c70"},
-    {file = "scikit_image-0.25.1-cp311-cp311-manylinux_2_17_aarch64.manylinux2014_aarch64.whl", hash = "sha256:0f5e313b028f5d7a9f3888ad825ddf4fb78913d7762891abb267b99244b4dd31"},
-    {file = "scikit_image-0.25.1-cp311-cp311-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:39ad76aeff754048dabaff83db752aa0655dee425f006678d14485471bdb459d"},
-    {file = "scikit_image-0.25.1-cp311-cp311-win_amd64.whl", hash = "sha256:8dc8b06176c1a2316fa8bc539fd7e96155721628ae5cf51bc1a2c62cb9786581"},
-    {file = "scikit_image-0.25.1-cp312-cp312-macosx_10_13_x86_64.whl", hash = "sha256:ebf83699d60134909647395a0bf07db3859646de7192b088e656deda6bc15e95"},
-    {file = "scikit_image-0.25.1-cp312-cp312-macosx_12_0_arm64.whl", hash = "sha256:408086520eed036340e634ab7e4f648e00238f711bac61ab933efeb11464a238"},
-    {file = "scikit_image-0.25.1-cp312-cp312-manylinux_2_17_aarch64.manylinux2014_aarch64.whl", hash = "sha256:5bd709faa87795869ccd21f32490c37989ca5846571495822f4b9430fb42c34c"},
-    {file = "scikit_image-0.25.1-cp312-cp312-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:a6b15c0265c072a46ff4720784d756d8f8e5d63567639aa8451f6673994d6846"},
-    {file = "scikit_image-0.25.1-cp312-cp312-win_amd64.whl", hash = "sha256:a689a0d091e0bd97d7767309abdeb27c43be210d075abb34e71657add920c22b"},
-    {file = "scikit_image-0.25.1-cp313-cp313-macosx_10_13_x86_64.whl", hash = "sha256:f070f899d6572a125ab106c4b26d1a5fb784dc60ba6dea45c7816f08c3a4fb4d"},
-    {file = "scikit_image-0.25.1-cp313-cp313-macosx_12_0_arm64.whl", hash = "sha256:cc9538d8db7670878aa68ea79c0b1796b6c771085e8d50f5408ee617da3281b6"},
-    {file = "scikit_image-0.25.1-cp313-cp313-manylinux_2_17_aarch64.manylinux2014_aarch64.whl", hash = "sha256:caa08d4fa851e1f421fcad8eac24d32f2810971dc61f1d72dc950ca9e9ec39b1"},
-    {file = "scikit_image-0.25.1-cp313-cp313-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:c9923aa898b7921fbcf503d32574d48ed937a7cff45ce8587be4868b39676e18"},
-    {file = "scikit_image-0.25.1-cp313-cp313-win_amd64.whl", hash = "sha256:6c7bba6773ab8c39ee8b1cbb17c7f98965bacdb8cd8da337942be6acc38fc562"},
-    {file = "scikit_image-0.25.1.tar.gz", hash = "sha256:d4ab30540d114d37c35fe5c837f89b94aaba2a7643afae8354aa353319e9bbbb"},
+    {file = "scikit_image-0.25.2-cp310-cp310-macosx_10_9_x86_64.whl", hash = "sha256:d3278f586793176599df6a4cf48cb6beadae35c31e58dc01a98023af3dc31c78"},
+    {file = "scikit_image-0.25.2-cp310-cp310-macosx_12_0_arm64.whl", hash = "sha256:5c311069899ce757d7dbf1d03e32acb38bb06153236ae77fcd820fd62044c063"},
+    {file = "scikit_image-0.25.2-cp310-cp310-manylinux_2_17_aarch64.manylinux2014_aarch64.whl", hash = "sha256:be455aa7039a6afa54e84f9e38293733a2622b8c2fb3362b822d459cc5605e99"},
+    {file = "scikit_image-0.25.2-cp310-cp310-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:a4c464b90e978d137330be433df4e76d92ad3c5f46a22f159520ce0fdbea8a09"},
+    {file = "scikit_image-0.25.2-cp310-cp310-win_amd64.whl", hash = "sha256:60516257c5a2d2f74387c502aa2f15a0ef3498fbeaa749f730ab18f0a40fd054"},
+    {file = "scikit_image-0.25.2-cp311-cp311-macosx_10_9_x86_64.whl", hash = "sha256:f4bac9196fb80d37567316581c6060763b0f4893d3aca34a9ede3825bc035b17"},
+    {file = "scikit_image-0.25.2-cp311-cp311-macosx_12_0_arm64.whl", hash = "sha256:d989d64ff92e0c6c0f2018c7495a5b20e2451839299a018e0e5108b2680f71e0"},
+    {file = "scikit_image-0.25.2-cp311-cp311-manylinux_2_17_aarch64.manylinux2014_aarch64.whl", hash = "sha256:b2cfc96b27afe9a05bc92f8c6235321d3a66499995675b27415e0d0c76625173"},
+    {file = "scikit_image-0.25.2-cp311-cp311-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:24cc986e1f4187a12aa319f777b36008764e856e5013666a4a83f8df083c2641"},
+    {file = "scikit_image-0.25.2-cp311-cp311-win_amd64.whl", hash = "sha256:b4f6b61fc2db6340696afe3db6b26e0356911529f5f6aee8c322aa5157490c9b"},
+    {file = "scikit_image-0.25.2-cp312-cp312-macosx_10_13_x86_64.whl", hash = "sha256:8db8dd03663112783221bf01ccfc9512d1cc50ac9b5b0fe8f4023967564719fb"},
+    {file = "scikit_image-0.25.2-cp312-cp312-macosx_12_0_arm64.whl", hash = "sha256:483bd8cc10c3d8a7a37fae36dfa5b21e239bd4ee121d91cad1f81bba10cfb0ed"},
+    {file = "scikit_image-0.25.2-cp312-cp312-manylinux_2_17_aarch64.manylinux2014_aarch64.whl", hash = "sha256:9d1e80107bcf2bf1291acfc0bf0425dceb8890abe9f38d8e94e23497cbf7ee0d"},
+    {file = "scikit_image-0.25.2-cp312-cp312-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:a17e17eb8562660cc0d31bb55643a4da996a81944b82c54805c91b3fe66f4824"},
+    {file = "scikit_image-0.25.2-cp312-cp312-win_amd64.whl", hash = "sha256:bdd2b8c1de0849964dbc54037f36b4e9420157e67e45a8709a80d727f52c7da2"},
+    {file = "scikit_image-0.25.2-cp313-cp313-macosx_10_13_x86_64.whl", hash = "sha256:7efa888130f6c548ec0439b1a7ed7295bc10105458a421e9bf739b457730b6da"},
+    {file = "scikit_image-0.25.2-cp313-cp313-macosx_12_0_arm64.whl", hash = "sha256:dd8011efe69c3641920614d550f5505f83658fe33581e49bed86feab43a180fc"},
+    {file = "scikit_image-0.25.2-cp313-cp313-manylinux_2_17_aarch64.manylinux2014_aarch64.whl", hash = "sha256:28182a9d3e2ce3c2e251383bdda68f8d88d9fff1a3ebe1eb61206595c9773341"},
+    {file = "scikit_image-0.25.2-cp313-cp313-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:b8abd3c805ce6944b941cfed0406d88faeb19bab3ed3d4b50187af55cf24d147"},
+    {file = "scikit_image-0.25.2-cp313-cp313-win_amd64.whl", hash = "sha256:64785a8acefee460ec49a354706db0b09d1f325674107d7fa3eadb663fb56d6f"},
+    {file = "scikit_image-0.25.2-cp313-cp313t-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:330d061bd107d12f8d68f1d611ae27b3b813b8cdb0300a71d07b1379178dd4cd"},
+    {file = "scikit_image-0.25.2.tar.gz", hash = "sha256:e5a37e6cd4d0c018a7a55b9d601357e3382826d3888c10d0213fc63bff977dde"},
 ]
 
 [package.dependencies]
@@ -8427,16 +8491,16 @@ networkx = ">=3.0"
 numpy = ">=1.24"
 packaging = ">=21"
 pillow = ">=10.1"
-scipy = ">=1.11.2"
+scipy = ">=1.11.4"
 tifffile = ">=2022.8.12"
 
 [package.extras]
-build = ["Cython (>=3.0.8)", "build (>=1.2.1)", "meson-python (>=0.16)", "ninja (>=1.11.1.1)", "numpy (>=2.0)", "pythran (>=0.16)", "setuptools (>=68)", "spin (==0.13)"]
+build = ["Cython (>=3.0.8)", "build (>=1.2.1)", "meson-python (>=0.16)", "ninja (>=1.11.1.1)", "numpy (>=2.0)", "pythran (>=0.16)", "spin (==0.13)"]
 data = ["pooch (>=1.6.0)"]
 developer = ["ipython", "pre-commit", "tomli"]
-docs = ["PyWavelets (>=1.6)", "dask[array] (>=2022.9.2)", "intersphinx-registry (>=0.2411.14)", "ipykernel", "ipywidgets", "kaleido (==0.2.1)", "matplotlib (>=3.7)", "myst-parser", "numpydoc (>=1.7)", "pandas (>=2.0)", "plotly (>=5.20)", "pooch (>=1.6)", "pydata-sphinx-theme (>=0.16)", "pytest-doctestplus", "scikit-learn (>=1.2)", "seaborn (>=0.11)", "sphinx (>=8.0)", "sphinx-copybutton", "sphinx-gallery[parallel] (>=0.18)", "sphinx_design (>=0.5)", "tifffile (>=2022.8.12)"]
-optional = ["PyWavelets (>=1.6)", "SimpleITK", "astropy (>=5.0)", "cloudpickle (>=0.2.1)", "dask[array] (>=2021.1.0,!=2024.8.0)", "matplotlib (>=3.7)", "pooch (>=1.6.0)", "pyamg (>=5.2)", "scikit-learn (>=1.2)"]
-test = ["asv", "numpydoc (>=1.7)", "pooch (>=1.6.0)", "pytest (>=7.0)", "pytest-cov (>=2.11.0)", "pytest-doctestplus", "pytest-faulthandler", "pytest-localserver"]
+docs = ["PyWavelets (>=1.6)", "dask[array] (>=2023.2.0)", "intersphinx-registry (>=0.2411.14)", "ipykernel", "ipywidgets", "kaleido (==0.2.1)", "matplotlib (>=3.7)", "myst-parser", "numpydoc (>=1.7)", "pandas (>=2.0)", "plotly (>=5.20)", "pooch (>=1.6)", "pydata-sphinx-theme (>=0.16)", "pytest-doctestplus", "scikit-learn (>=1.2)", "seaborn (>=0.11)", "sphinx (>=8.0)", "sphinx-copybutton", "sphinx-gallery[parallel] (>=0.18)", "sphinx_design (>=0.5)", "tifffile (>=2022.8.12)"]
+optional = ["PyWavelets (>=1.6)", "SimpleITK", "astropy (>=5.0)", "cloudpickle (>=1.1.1)", "dask[array] (>=2023.2.0)", "matplotlib (>=3.7)", "pooch (>=1.6.0)", "pyamg (>=5.2)", "scikit-learn (>=1.2)"]
+test = ["asv", "numpydoc (>=1.7)", "pooch (>=1.6.0)", "pytest (>=8)", "pytest-cov (>=2.11.0)", "pytest-doctestplus", "pytest-faulthandler", "pytest-localserver"]
 
 [[package]]
 name = "scikit-learn"
@@ -9206,14 +9270,14 @@ files = [
 
 [[package]]
 name = "tifffile"
-version = "2025.1.10"
+version = "2025.2.18"
 description = "Read and write TIFF files"
 optional = false
 python-versions = ">=3.10"
 groups = ["evaluation"]
 files = [
-    {file = "tifffile-2025.1.10-py3-none-any.whl", hash = "sha256:ed24cf4c99fb13b4f5fb29f8a0d5605e60558c950bccbdca2a6470732a27cfb3"},
-    {file = "tifffile-2025.1.10.tar.gz", hash = "sha256:baaf0a3b87bf7ec375fa1537503353f70497eabe1bdde590f2e41cc0346e612f"},
+    {file = "tifffile-2025.2.18-py3-none-any.whl", hash = "sha256:54b36c4d5e5b8d8920134413edfe5a7cfb1c7617bb50cddf7e2772edb7149043"},
+    {file = "tifffile-2025.2.18.tar.gz", hash = "sha256:8d731789e691b468746c1615d989bc550ac93cf753e9210865222e90a5a95d11"},
 ]
 
 [package.dependencies]
@@ -10789,4 +10853,4 @@ testing = ["coverage[toml]", "zope.event", "zope.testing"]
 [metadata]
 lock-version = "2.1"
 python-versions = "^3.12"
-content-hash = "14998d54438fedacad9d82422003f46d0d7721bd50c2f8096657c15dce0f3edd"
+content-hash = "39e0f069346a4d1e52193899989b79ea3e02f81d67fbb2ac0fdc87e70bd1008f"
diff --git a/pyproject.toml b/pyproject.toml
index 8cc47ebaeb0a..b8919d936deb 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -76,6 +76,7 @@ stripe = "^11.5.0"
 ipywidgets = "^8.1.5"
 qtconsole = "^5.6.1"
 memory-profiler = "^0.61.0"
+daytona-sdk = "0.9.1"
 
 [tool.poetry.group.llama-index.dependencies]
 llama-index = "*"
diff --git a/tests/runtime/conftest.py b/tests/runtime/conftest.py
index 73b18680a11e..bb0c1eca696b 100644
--- a/tests/runtime/conftest.py
+++ b/tests/runtime/conftest.py
@@ -11,6 +11,7 @@
 from openhands.core.logger import openhands_logger as logger
 from openhands.events import EventStream
 from openhands.runtime.base import Runtime
+from openhands.runtime.impl.daytona.daytona_runtime import DaytonaRuntime
 from openhands.runtime.impl.docker.docker_runtime import DockerRuntime
 from openhands.runtime.impl.local.local_runtime import LocalRuntime
 from openhands.runtime.impl.remote.remote_runtime import RemoteRuntime
@@ -130,6 +131,8 @@ def get_runtime_classes() -> list[type[Runtime]]:
         return [RemoteRuntime]
     elif runtime.lower() == 'runloop':
         return [RunloopRuntime]
+    elif runtime.lower() == 'daytona':
+        return [DaytonaRuntime]
     else:
         raise ValueError(f'Invalid runtime: {runtime}')
 
diff --git a/tests/unit/test_config.py b/tests/unit/test_config.py
index 10f09447ba6c..0848dda676de 100644
--- a/tests/unit/test_config.py
+++ b/tests/unit/test_config.py
@@ -686,6 +686,7 @@ def test_api_keys_repr_str():
         modal_api_token_id='my_modal_api_token_id',
         modal_api_token_secret='my_modal_api_token_secret',
         runloop_api_key='my_runloop_api_key',
+        daytona_api_key='my_daytona_api_key',
     )
     assert 'my_e2b_api_key' not in repr(app_config)
     assert 'my_e2b_api_key' not in str(app_config)
@@ -697,6 +698,8 @@ def test_api_keys_repr_str():
     assert 'my_modal_api_token_secret' not in str(app_config)
     assert 'my_runloop_api_key' not in repr(app_config)
     assert 'my_runloop_api_key' not in str(app_config)
+    assert 'my_daytona_api_key' not in repr(app_config)
+    assert 'my_daytona_api_key' not in str(app_config)
 
     # Check that no other attrs in AppConfig have 'key' or 'token' in their name
     # This will fail when new attrs are added, and attract attention
@@ -705,6 +708,7 @@ def test_api_keys_repr_str():
         'modal_api_token_id',
         'modal_api_token_secret',
         'runloop_api_key',
+        'daytona_api_key',
     ]
     for attr_name in AppConfig.model_fields.keys():
         if (