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Add additional options for peak callers #62

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j-andrews7 opened this issue Nov 9, 2021 · 1 comment
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Add additional options for peak callers #62

j-andrews7 opened this issue Nov 9, 2021 · 1 comment
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@chris-cheshire @tamara-hodgetts
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enhancement Improvement for existing functionality WIP Work in progress

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@j-andrews7
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Is your feature request related to a problem? Please describe

SEACR has limited parameters to play with to adjust peak calling. It tends to be overly sensitive in our hands, and it has no good metrics for downstream peak filtering,

Describe the solution you'd like

Additional options for peakcallers (MACS, MACS2, etc) would be appreciated and allow for consensus and thresholding approaches to deal with false positives downstream. Being able to run more than one peakcaller would be an added bonus.
@j-andrews7 j-andrews7 added the enhancement Improvement for existing functionality label Nov 9, 2021
@chris-cheshire chris-cheshire added the WIP Work in progress label Jan 4, 2022
@chris-cheshire
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Hi @j-andrews7 , we have added MACS2 as an additional peak caller in v2.0

@chris-cheshire chris-cheshire mentioned this issue May 6, 2022
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@chris-cheshire @j-andrews7 @tamara-hodgetts