Here are various tutorials for using the Trendy Bioconductor package for segmented regression analysis of expression dynamics for high-throughput ordered profiling experiments.
-- a tutorial for using Trendy on single-cell RNA-seq data that has been computationally reordered.
http://www.bioconductor.org/packages/release/bioc/vignettes/Trendy/inst/doc/Trendy_vignette.pdf